D-dimer for VTE in CoVID

Ref: Journalfeed.

Can we trust D-dimer for VTE in CoVID?

Multicenter retrospective observational study, n=1158.
CTPA + D-dimer
D-dimer within 24hrs of CTPA (not always prior to)
For CoVID+: Sens 100% (ie. all with d-dim>cutoff +PE), spec 11.9%. NPV 100%.
CoViD-: sens 97.6%, spec 14.4%, NPV 98.3%.
Suggested CoVID-adjusted cutoffs for D-dimer: 0.5mg/L -> 0.67mg/L. Maintained NPV 100%, while specificity rose to 28%.